Glyco-Flex II is formulated for adult and maturing dogs, especially sporting and working breeds. Additional ingredients include methylsulfonylmethane (MSM) and manganese, a mineral synergist of glucosamine.Suggested initial use: 1/2 tablet or one chew daily per 30 lbs of body weight. For dogs requiring more than one tablet or chew, divide between a.m. and p.m.