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Interceptor Rx, Green (Dog 11-25lbs) and (Cat 1.5-6 lbs)
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PRESCRIPTION REQUIRED. Interceptor RX is a tablet that prevents heartworm disease, controls adult hookworm, and removes and controls adult roundworm and whipworm infections in dogs and puppies. Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
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Bulk supply needs? please call us at 1-877-247-4633 or email
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Interceptor Rx, (Dog 11-25lbs) and (Cat 1.5-6 lbs) Green, 6
Month
Call for Volume Discounts
INTERCEPTOR® FLAVOR TABS®
Rx
Novartis
(milbemycin oxime)
Interceptor Rx, Green, (Dog 11-25lbs)and (Cat 1.5-6 lbs), 6 Month
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INFORMATION FOR DOSING DOGS
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The palatable once-a-month tablet that prevents heartworm disease, controls
adult hookworm, and removes and controls adult roundworm and whipworm
infections in dogs and puppies.
Description:
INTERCEPTOR (milbemycin oxime) Flavor Tabs are
available in four tablet sizes in color-coded packages for oral administration
to dogs and puppies. Each tablet is formulated to provide a minimum of 0.23
mg/lb (0.5 mg/kg) body weight of milbemycin oxime. Milbemycin oxime consists
of the oxime derivatives of 5-didehydromilbemycins in the ratio of
approximately 80% A4 (C32H45NO7, MW 555.71) and 20% A3 (C31H43NO7, MW 541.68).
Package color Milbemycin oxime tablet Brown 2.3 mg Green 5.75 mg Yellow 11.5
mg White 23.0 mg Indications: INTERCEPTOR Flavor Tabs are indicated for use in
the prevention of heartworm disease caused by Diroflaria immitis, the control
of adult Ancylostoma caninum (hookworm), and the removal and control of adult
Toxocara canis and Toxascaris leonina (roundworms) and (whipworm) infections
in dogs and in puppies four weeks of age or greater and two pounds body weight
or greater. Dosage: INTERCEPTOR Flavor Tabs are given orally, once a month, at
the recommended minimum dosage rate of 0.23 mg milbemycin oxime per pound of
body weight (0.5mg/kg). Recommended Dosage Schedule for Dogs
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Body Weight
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Flavor Tab
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2-10 lbs.
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One tablet (2.3 mg)
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11-25 lbs.
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One tablet (5.75 mg)
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26-50 lbs.
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One tablet (11.5 mg)
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51-100 lbs.
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One tablet (23.0 mg)
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Dogs over 100 lbs. are provided the appropriate combination of tablets.
Administration:
INTERCEPTOR Flavor Tabs are palatable and
most dogs will consume the tablet willingly when offered by the owner. As an
alternative, the dual-purpose tablet may be offered in food or administered as
other tablet medications. Watch the dog closely following dosing to be sure
the entire dose has been consumed. If it is not entirely consumed, redose once
with the full recommended dose as soon as possible. INTERCEPTOR Flavor Tabs
must be administered monthly, preferably on the same date each month. The
first dose should be administered within one month of the dog’s first exposure
to mosquitoes and monthly thereafter until the end of the mosquito season. If
a dose is missed and a 30-day interval between dosing is exceeded, administer
INTERCEPTOR Flavor Tabs immediately and resume the monthly dosing schedule. If
INTERCEPTOR Flavor Tabs replaces diethylcarbamazine (DEC) for heartworm
prevention, the first dose must be given within 30 days after the last dose of
DEC.
Palatability:
Palatability trials conducted in 244 dogs from
10 different U.S. veterinary practices demonstrated that INTERCEPTOR Flavor
Tabs were willingly accepted from the owner by over 95% of dogs. The trial was
comprised of dogs representing 60 different breeds and both sexes, with
weights ranging from 2.1 lbs. to 143.3 lbs., and ages ranging from 8 weeks to
15 years.
Precautions:
Do not use in puppies less than four weeks of
age and less than two pounds of body weight. Prior to the initiation of the
INTERCEPTOR Flavor Tabs treatment program, dogs should be tested for existing
heartworm infections. Infected dogs should be treated to remove adult
heartworms and microfiliariae prior to initiating treatment with INTERCEPTOR
Flavor Tabs. Mild, transient hypersensitivity reactions manifested as labored
respiration, vomiting, salivation and lethargy, have been noted in some
treated dogs carrying a high number of circulating microfilariae. These
reactions are presumably caused by release of protein from dead or dying
microfilariae.
Adverse Reactions:
The following adverse reactions have been
reported following the use of INTERCEPTOR: Depression/lethargy, vomiting,
ataxia, anorexia, diarrhea, convulsions, weakness and hypersalivation.
Efficacy:
INTERCEPTOR Flavor Tabs eliminate the tissue
stage of heartworm larvae and the adult stage of hookworm (Ancylostoma
caninum), roundworms (Toxocara canis, Toxascaris leonina) and whipworm
(Trichuris vulpis) infestations when administered orally according to the
recommended dosage schedule. The anthelmintic activity of milbemycin oxime is
believed to be a result of interference with invertebrate neurotransmission.
Safety:
INTERCEPTOR has been tested safely in over 75
different breeds of dogs, including collies, pregnant females, breeding males
and females, and puppies over two weeks of age. In well-controlled clinical
field studies 786 dogs completed treatment with milbemycin oxime. Milbemycin
oxime was used safely in animals receiving frequently used veterinary products
such as vaccines, anthelmintics, antibiotics, steroids, flea collars, shampoos
and dips. Two studies in heartworm-infected dogs were conducted which
demonstrated mild, transient hypersensitivity reactions in treated dogs with
high microfilaremia counts (see Precautions for reactions observed). Safety
studies in pregnant dogs demonstrated that high doses (1.5 mg/kg = 3X) of
milbemycin oxime given in an exaggerated dosing regimen (daily from mating
through weaning), resulted in measurable concentrations of the drug in milk.
Puppies nursing these females which received exaggerated dosing regimens
demonstrated milbemycin-related effects. These effects were directly
attributable to the exaggerated experimental dosing regimen. The product is
normally intended for once-a-month administration only. Subsequent studies
included using 3X daily from mating to one week before weaning and
demonstrated no effects on the pregnant females or their litters. A second
study where pregnant females were dosed once at 3X the monthly use rate either
before, on the day of or shortly after whelping resulted in no effects on the
puppies. Some nursing puppies, at 2, 4, and 6 weeks of age, given greatly
exaggerated oral INTERCEPTOR doses (9.6 mg/kg = 19X) exhibited signs typified
by tremors, vocalization and ataxia. These effects were all transient and
puppies returned to normal within 24 to 48 hours. No effects were observed in
puppies given the recommended dose of INTERCEPTOR (0.5 mg/kg). This product
has not been tested in dogs less than 1 kg weight. A rising-dose safety study
conducted in roughcoated collies, manifested a clinical reaction consisting of
ataxia, pyrexia and periodic recumbency, in one of fourteen dogs treated with
milbemycin oxime at 12.5 mg/kg (25X monthly use rate). Prior to receiving the
12.5 mg/kg dose (25X monthly use rate) on day 56 of the study, all animals had
undergone an exaggerated dosing regimen consisting of 2.5 mg/kg milbemycin
oxime (5X monthly use rate) on day 0, following by 5.0 mg/kg (10X monthly use
rate) on day 14 and 10.0 mg/kg (20X monthly use rate) on day 32. No adverse
reactions were observed in any of the collies treated with this regimen up
through the 10.0 mg/kg (20X monthly use rate) dose.
How supplied:
INTERCEPTOR Flavor Tabs are available in four
tablet sizes (see Dosage section), formulated according to the weight of the
dog. Each tablet size is available in color-coded packages of 6 or 12 tablets
each, which are packaged 10 per display carton.
Storage conditions:
INTERCEPTOR Flavor Tabs should be stored at
room temperature, between 59° and 86°F (15-30°C)
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INFORMATION FOR DOSING CATS
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The palatable once-a-month tablet that prevents heartworm disease and
removes adult roundworms and hookworms in cats and kittens.
Description:
INTERCEPTOR Flavor Tabs for Cats are
available in three tablet sizes in color-coded packages for oral
administration to cats and kittens. Each tablet is formulated to provide a
minimum of 0.9 mg/lb (2.0 mg/kg) body weight of milbemycin oxime. Milbemycin
oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio
of approximately 80% A4 (C32H45NO7, MW 555.71) and 20% A3 (C31H43NO7, MW
541.68).
Indications:
INTERCEPTOR Flavor Tabs for Cats are
indicated for use in the prevention of heartworm disease caused by Dirofilaria
immitis, and the removal of adult Ancytostoma tubaeforme (hookworm)
and Toxocara cati (roundworm) in cats and kittens six weeks of age or
greater and 1.5 lbs. body weight or greater.
Dosage:
INTERCEPTOR Flavor Tabs for Cats are given
orally, once a month, at the recommended minimum dosage rate of 0.9 mg
milbemycin oxime per pound of body weight (2.0mg/kg).
Recommended Dosage Schedule for Cats
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Body Weight
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Flavor Tab
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1.5 to 6 lbs.
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One tablet (5.75 mg)
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6.1 to 12 lbs.
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One tablet (11.5 mg)
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12.1 to 25 lbs.
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One tablet (23.0 mg)
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Cats over 25 lbs. are provided the appropriate combination of tablets.
Administration:
INTERCEPTOR Flavor Tabs for Cats are
palatable and may be offered by the owner as a treat. As an alternative, the
tablet may be offered in food or administered as other tablet medications. The
tablets can be broken for ease of administration. Watch the cat closely
following dosing to be sure the entire dose has been consumed. If it is not
entirely consumed, redose once with the full recommended dose as soon as
possible.
INTERCEPTOR Flavor Tabs for Cats must be administered monthly,
preferably on the same date each month. The first dose should be administered
within one month of the cat’s first exposure to mosquitoes and monthly
thereafter until the end of the mosquito season. If a dose is missed and a
30-day interval between dosing is exceeded, administer INTERCEPTOR Flavor Tabs
for Cats immediately and resume the monthly dosing schedule. It is recommended
that cats be tested for existing heartworm infection prior to starting
treatment with Flavor Tabs for Cats (See Precautions).
Palatability:
Palatability trials conducted in 72 cats
demonstrated that INTERCEPTOR Flavor Tabs for Cats were successfully dosed by
the owner when they either offered the tablet as a treat, placed the tablet in
the cat’s mouth or placed the tablet in the cat’s food in 72% of cats. About
16% of the cats were manually dosed and 13% of the cats were not successfully
dosed according to the protocol.
Precautions:
Do not use in kittens less than six weeks
of age or less than 1.5 lbs. body weight. Safety in heartworm positive cats
has not been established. Safety in breeding, pregnant, and lactating queens
and breeding toms has not been established.
Efficacy:
INTERCEPTOR Flavor Tabs for Cats eliminate
the tissue stage of heartworm larvae and hookworm (Ancylostoma tubaeforme)
and roundworm (Toxocara cati) infections when administered orally
according to the recommended dosage schedule. The anthelmintic activity of
milbemycin oxime is believed to be a result of interference with invertebrate
neurotransmission.
Safety:
INTERCEPTOR Flavor Tabs for Cats has been
tested safely in over 8 different breeds of cats. In well-controlled clinical
field studies 141 cats completed treatment with milbemycin oxime. Milbemycin
oxime was used safely in animals receiving frequently used veterinary products
such as vaccines, anthelmintics, anesthetics, antibiotics, steroids, flea
collars, shampoos and dips.
Safety studies were conducted in young cats and kittens and doses of 1X,
3X and 5X the minimum recommended dose of 2.0 mg/kg demonstrated no
drug-related effects. Tolerability studies at exaggerated doses of 10X also
demonstrated no drug-related adverse effects in kittens and young adult cats.
How supplied:
INTERCEPTOR Flavor Tabs for Cats are
available in three tablet sizes (see Dosage section), formulated according to
the weight of the cat. Each tablet size is available in color-coded packages
of 6 or 12 tablets each, which are packaged 10 per display carton.
Storage conditions:
INTERCEPTOR Flavor Tabs for Cats should be
stored at room temperature, between 59° and 86°F (15-30°C)
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Click for order information
All Prices in US Dollars
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